(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(2,4,5-trifluorophenyl)butanoic acid
Fmoc-(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid
CAS: 1217818-53-5
Molecular Formula: C25H20F3NO4
(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(2,4,5-trifluorophenyl)butanoic acid - Names and Identifiers
(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(2,4,5-trifluorophenyl)butanoic acid - Physico-chemical Properties
| Molecular Formula | C25H20F3NO4 |
| Molar Mass | 455.43 |
| Storage Condition | 2-8°C |
(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(2,4,5-trifluorophenyl)butanoic acid - Introduction
Fmoc-(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid is an organic compound with the following properties:
1. Appearance: white to off-white crystalline powder.
2. molecular formula: C19H17F3NO4.
3. Molecular weight: 389.34g/mol.
4. Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dichloromethane, insoluble in water.
5. melting point: about 123-128 ℃.
Fmoc-(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid is mainly used for the following purposes:
1. Drug research and synthesis: As chemical reagents and intermediates in organic synthesis, it can be used to synthesize amino acid compounds.
2. protein chemistry: as a reagent for modifying and labeling amino acid residues, it is commonly used in peptide synthesis in solid phase synthesis.
The preparation method of Fmoc-(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid can be roughly divided into the following steps:
1.3-carboxy-4-(2,4, 5-trifluorophenyl) butyric acid and Fmoc-Cl (Fmoc acid chloride salt of dimethylamine) are reacted under alkaline conditions to obtain Fmoc-(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid.
2. The product was purified and crystallized to obtain the pure product.
Regarding safety information, specific toxicity and hazard data of Fmoc-(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid have not been publicly reported. However, as chemical reagents, general laboratory safety procedures should be followed, including wearing appropriate personal protective equipment (such as gloves, glasses and laboratory clothes), avoiding direct contact with skin and eyes, avoiding inhalation or intake, and Ensure that the compound is used under well-ventilated conditions. In case of contact or misuse, should promptly seek medical attention and provide material safety data sheet (MSDS). In the process of handling and storage, please understand the physical and chemical properties and safety data of the compound in detail.
1. Appearance: white to off-white crystalline powder.
2. molecular formula: C19H17F3NO4.
3. Molecular weight: 389.34g/mol.
4. Solubility: Soluble in organic solvents such as dimethyl sulfoxide and dichloromethane, insoluble in water.
5. melting point: about 123-128 ℃.
Fmoc-(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid is mainly used for the following purposes:
1. Drug research and synthesis: As chemical reagents and intermediates in organic synthesis, it can be used to synthesize amino acid compounds.
2. protein chemistry: as a reagent for modifying and labeling amino acid residues, it is commonly used in peptide synthesis in solid phase synthesis.
The preparation method of Fmoc-(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid can be roughly divided into the following steps:
1.3-carboxy-4-(2,4, 5-trifluorophenyl) butyric acid and Fmoc-Cl (Fmoc acid chloride salt of dimethylamine) are reacted under alkaline conditions to obtain Fmoc-(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid.
2. The product was purified and crystallized to obtain the pure product.
Regarding safety information, specific toxicity and hazard data of Fmoc-(R)-3-Amino-4-(2,4,5-trifluoro-phenyl)-butyric acid have not been publicly reported. However, as chemical reagents, general laboratory safety procedures should be followed, including wearing appropriate personal protective equipment (such as gloves, glasses and laboratory clothes), avoiding direct contact with skin and eyes, avoiding inhalation or intake, and Ensure that the compound is used under well-ventilated conditions. In case of contact or misuse, should promptly seek medical attention and provide material safety data sheet (MSDS). In the process of handling and storage, please understand the physical and chemical properties and safety data of the compound in detail.
Last Update：2024-04-09 20:45:29
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